Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
US10239846B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jan 13, 2017 |
| Grant date | Mar 26, 2019 |
| Priority date | — |
| Expiry date | Jan 13, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.