Patent · US Active

Synthesis of resorcylic acid lactones useful as therapeutic agents

US10239856B2 · kind B2 · utility

1Cited by
4References
19Claims
0Family size

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Inventors

Key dates

Filing dateApr 21, 2015
Grant dateMar 26, 2019
Priority date
Expiry dateApr 21, 2035

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are macrocyclic compounds of formulae I, I′, II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.