Use of dimerization domains for temperature regulation of enzyme activity
US10240137B2 · kind B2 · utility
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Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Mar 26, 2019 |
| Priority date | — |
| Expiry date | Mar 14, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01008
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for regulating protein activity by fusing dimerization domains to target protein are provided. Chimeric proteins that include dimerization domains fused to target proteins for altering the activity of the target proteins are described. Engineered nucleic acids encoding chimeric proteins and hosts engineered to express engineered nucleic acids are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.