Method for the production of protein complexes and vaccine compositions comprising the same
US10240179B2 · kind B2 · utility
1Cited by
3References
23Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 23, 2012 |
| Grant date | Mar 26, 2019 |
| Priority date | — |
| Expiry date | Mar 23, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for the production of heat shock protein complexes for use in vaccine compositions. In particular, there is provided a method for increasing the level and immunogenicity of heat shock protein complexes produced in cells by subjecting the cells to specific stress inducing stimuli. The invention further extends to the use of heat shock protein complexes produced according to the methods of the invention in the preparation of vaccine compositions for the prevention and treatment of infectious diseases and cancerous conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.