Chemical methods for producing tagged nucleotides

US10240195B2 · kind B2 · utility

Assignees

• The Trustees of Columbia University in the City of New York · US
• Genia Technologies, Inc. · US

Inventors

• Carl W. Fuller · Cleveland Heights, US
• Shiv Kumar · Montgomery, US
• Jingyue Ju · Englewood Cliffs, US
• Randall Davis · Pleasanton, US
• Roger Chen · Saratoga, US

Key dates

• Filing date: Mar 23, 2015
• Grant date: Mar 26, 2019
• Expiry date: Mar 7, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6869
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This disclosure provides systems and methods for attaching nanopore-detectable tags to nucleotides. The disclosure also provides methods for sequencing nucleic acids using the disclosed tagged nucleotides.