Biological tissue analysis by inverse spectroscopic optical coherence tomography
US10241041B2 · kind B2 · utility
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Key dates
| Filing date | May 9, 2017 |
| Grant date | Mar 26, 2019 |
| Priority date | — |
| Expiry date | May 9, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01B9/02091
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio or scattering coefficient μs, and the back-scattering coefficient μb), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.
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