Non-CRISPR-mediated phage resistant Streptococcus thermophilus
US10244771B2 · kind B2 · utility
0Cited by
0References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 23, 2015 |
| Grant date | Apr 2, 2019 |
| Priority date | — |
| Expiry date | Jul 23, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/11
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method for the construction of a bacteriophage-insensitive mutant of a Streptococcus thermophilus parent strain whereby the bacteriophage insensitivity is not based on the CRISPR resistance mechanism but based on another mechanism. The method provides a protocol by which this can be achieved by inactivating one or more of the CRISPR systems present in a given strain. The invention also provides the bacteriophage-insensitive mutants as well as their use in a process for making a dairy product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.