Immunological reagents and uses therefor

US10245262B2 · kind B2 · utility

Assignees

• The University Of Queensland · AU
• MONASH UNIVERSITY · AU
• The University of Melbourne · AU

Inventors

• Alexandra Jane Corbett · Elmore, AU
• James McCluskey · Melbourne, AU
• Lars Kjer-Nielsen · Melbourne, AU
• Zhenjun Chen · Elmore, AU
• Jamie Rossjohn · Elmore, AU
• Onisha Patel · Elmore, AU
• Richard William Birkinshaw · Elmore, AU
• Sidonia Barbara Guiomar Eckle · Elmore, AU
• David Fairlie · Faulconbridge, AU
• Ligong Liu · Calle de la Era, AU
• Jeffrey Yam Wing Mak · Forsayth, AU

Key dates

• Filing date: Apr 1, 2015
• Grant date: Apr 2, 2019
• Expiry date: Apr 1, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/26
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides ligands which bind to MR1, some of which induce MR1 to bind to MAIT cells thereby activating or inhibiting MAIT cell activation.