Neuroactive steroids, compositions, and uses thereof
US10246482B2 · kind B2 · utility
34Cited by
31References
85Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 18, 2015 |
| Grant date | Apr 2, 2019 |
| Priority date | — |
| Expiry date | Jun 18, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J21/008
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described herein are steroids of Formula (I): and pharmaceutically acceptable salts thereof; wherein R1, R2a, R2b, R3, R4, R5a, R5b, R6, and Z are as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.