Patent · US Active

Conotoxin peptide κ-CPTX-BTL02, preparation method therefor, and uses thereof

US10246490B2 · kind B2 · utility

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0References

4Claims

0Family size

Assignee

BGI SHENZHEN · CN

Inventors

Jie Liu · Houston, US
Zhilong Lin · Tangxia, CN
Bo Wen · Tangxia, CN
Ting Tong · Tangxia, CN
Fen Mo · Tangxia, CN
Chao-Chun Peng · Chongqing, CN
Qiong Shi · Tangxia, CN

Key dates

Filing date	Dec 26, 2014
Grant date	Apr 2, 2019
Priority date	—
Expiry date	Dec 26, 2034

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided is a new conotoxin peptide κ-CPTx-btl02. The conotoxin peptide κ-CPTx-btl02 has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1, or has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1 and that is formed after substitution, addition or deletion of one or more amino acids are performed and has original functions. Also provided is polynucleotide for coding the peptide, comprising a constructed body of the polynucleotide, an expression carrier and transformed cells. A peptide preparation method and uses in the treatment of diseases related to a calcium ion channel.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.