Assay and method for quantitating carbonic anhydrase activity and assessing red blood hemolysis
US10246733B2 · kind B2 · utility
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Key dates
| Filing date | Jun 6, 2016 |
| Grant date | Apr 2, 2019 |
| Priority date | — |
| Expiry date | Jun 6, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/988
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method and assay for using carbonic anhydrase (CA), particularly CA-I or CA-II, as a biomarker of hemolysis. The method and assay detect hemolysis by determining a percentage erythrocyte hemolysis in a specimen or sample of blood based upon quantification of carbonic anhydrase present in the extracellular portion of the blood. The method and test serve to optimize therapeutic efficacy for treatments of hemolysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.