Patent · US Active

Kits for classifying a subject having or at risk for developing idiopathic scoliosis

US10247737B2 · kind B2 · utility

0Cited by
7References
18Claims
0Family size

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Key dates

Filing dateSep 9, 2014
Grant dateApr 2, 2019
Priority date—
Expiry dateSep 9, 2034

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/52
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method of classifying a subject having idiopathic scoliosis (IS) or at risk of developing IS comprising: determining the cellular response to Gi stimulation in a cell sample from the subject in the presence of OPN; determining the cellular response to Gi stimulation in a cell sample from the subject in the absence of OPN; and comparing the cellular response obtained in the presence of OPN with the cellular response obtained in the absence of OPN, whereby the comparing step enables the classification of the subject into one IS functional group. Also provided is the use of the foregoing method to classify borderline subjects and kits for applying the methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.