Glycan sample preparation
US10247745B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 27, 2015 |
| Grant date | Apr 2, 2019 |
| Priority date | — |
| Expiry date | Apr 27, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/38
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present teachings relate to methods, systems, and kits for the preparation, purification and/or analysis of a glycan or glycoconjugate, and specifically to a magnetic bead based sample preparation protocol that can enable full automation and reduced sample preparation time relative to current methods of glycoanalysis. In some aspects, the sample preparation protocol can provide for glycoconjugate capture, glycan release, fluorescent derivatization, and glycan purification for subsequent capillary electrophoresis, liquid chromatography, or other glycoanalytical method without requiring time-consuming sample preparation steps such as centrifugation or vacuum-centrifugation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.