Proteins for the treatment of epithelial barrier function disorders
US10251933B2 · kind B2 · utility
3Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 2018 |
| Grant date | Apr 9, 2019 |
| Priority date | — |
| Expiry date | Apr 6, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.