Patent · US Active

Stabilized HIV-1 peptide constructs comprising the gp120 C5 domain and gp41 hydrophilic domain

US10251949B2 · kind B2 · utility

0Cited by

1References

11Claims

0Family size

Assignee

BIONOR IMMUNO AS · NO

Inventors

Maja Sommerfelt Grønvold · Risør, NO
Angus Dalgleish · London, GB
Einar Tønnes Lange · Skien, NO
Jens Olof Holmberg · Helsingborg, SE
Per Bengtsson · Malmö, SE
Birger Sørensen · Vejle, DK

Key dates

Filing date	Nov 25, 2015
Grant date	Apr 9, 2019
Priority date	—
Expiry date	Jan 9, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/16171
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a method for treatment of HIV related diseases comprising targeting complexes between on the one hand the C5 domain of gp120 and on the other hand gp41 or the C2 domain of gp120. The complexes may be stabilised by administering compounds, such as antibodies, capable of directly interacting with and stabilising the complex, or by immunizing with C5 and gp41/C2 derived material so as to induce antibodies that bind to and stabilise the complex.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.