Patent · US Active

Process for preparing alkyl esters of 4-(5-(bis(2-hydroxyethyl)amino-1-methyl-1H-benzo[D]imidazol-2-yl)butyric acid

US10252999B2 · kind B2 · utility

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10Claims

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Assignee

Johnson Matthey Public Limited Company · GB

Inventors

Xing Fu · Longbeilingcun, CN
Saroop Singh Matharu · Shirley, US

Key dates

Filing date	Dec 18, 2017
Grant date	Apr 9, 2019
Priority date	—
Expiry date	Dec 18, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D235/16
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

An alkyl ester of 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid, such as ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, is obtained by reacting an alkyl ester of 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butyric acid with 2-hydroxyacetaldehyde under reducing conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.