Aryl lactam kinase inhibitors

US10253027B2 · kind B2 · utility

Assignees

• Syngene International Limited · IN
• Bristol-Myers Squibb Company · US

Inventors

• Richard A. Hartz · Kennett Square, US
• Vijay T. Ahuja · Middletown, US
• Joanne J. Bronson · Madison, US
• Carolyn Diane Dzierba · Middletown, US
• John E. Macor · Guilford, US
• Susheel Jethanand Nara · Mumbai, IN
• Ramkumar Rajamani · Wallingford, US

Key dates

• Filing date: Jul 1, 2014
• Grant date: Apr 9, 2019
• Expiry date: Jul 1, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.