WT1 antigenic polypeptide, and anti-tumor agent containing said polypeptide
US10253075B2 · kind B2 · utility
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Key dates
| Filing date | Feb 26, 2015 |
| Grant date | Apr 9, 2019 |
| Priority date | — |
| Expiry date | Feb 26, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1121
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
[Problem] To provide a polypeptide which enables stimulation of numerous T cells of different derivation, and to induce strong immunological response against numerous types of cancers.[Solution] Provided is a fused polypeptide that includes a helper epitope derived from the WT1 protein, and a killer epitope derived from the WT1 protein, wherein the polypeptide includes a total of 3 to 6 of the helper epitopes and the killer epitopes per molecule of the fused polypeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.