Patent · US Active

Glyco-engineered antibodies

US10253098B2 · kind B2 · utility

0Cited by

1References

11Claims

0Family size

Assignee

GREENOVATION BIOTECH GMBH · DE

Inventors

Manfred Schuster · Schrick, AT
Ralf Kircheis · Wien, AT
Andreas Nechansky · Oberwaltersdorf, AT
Wolfgang Jost · Glückstadt, DE
Gilbert Gorr · Glückstadt, DE

Key dates

Filing date	May 28, 2015
Grant date	Apr 9, 2019
Priority date	—
Expiry date	May 28, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/76
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.