Patent · US Active

Antibody fragments against the insulin receptor and uses thereof to treat hypoglycemia

US10253101B2 · kind B2 · utility

0Cited by

35References

33Claims

0Family size

Assignee

XOMA (US) LLC · US

Inventors

Paul Rubin · Sudbury, US
Toshihiko Takeuchi · Oakland, US
Hassan Issafras · Berkeley, US
Kiranjit Kaur Ahluwalia · Fremont, US
John Corbin · Oakland, US
Ira D. Goldfine · Poway, US
Kirk W. Johnson · Berkeley, US
Ou Li · San Francisco, US
Daniel Bedinger · Vacaville, US

Key dates

Filing date	Aug 5, 2016
Grant date	Apr 9, 2019
Priority date	—
Expiry date	Aug 21, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates, in general, to methods of treating or preventing hypoglycemia using a negative modulator antibody fragment that binds to the insulin receptor and modulates the action of insulin at the insulin receptor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.