Fluorogenic pH-sensitive dyes and their methods of use (II)
US10253185B2 · kind B2 · utility
0Cited by
5References
3Claims
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Key dates
| Filing date | Feb 3, 2017 |
| Grant date | Apr 9, 2019 |
| Priority date | — |
| Expiry date | Feb 3, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/84
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are compounds, compositions, methods and kits for detecting pH in samples using pH-sensitive fluorescent dyes. The compounds disclosed herein are novel xanthene-derivative dyes comprising an aniline moiety with one or more electron donating groups, which dyes are for detecting pH in samples either in vitro or in vivo. Also described herein are processes for preparing said dyes for use in the disclosed compositions, methods and kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.