Bouvardin derivatives and therapeutic uses thereof
US10259846B2 · kind B2 · utility
1Cited by
13References
24Claims
0Family size
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Key dates
| Filing date | Aug 10, 2016 |
| Grant date | Apr 16, 2019 |
| Priority date | — |
| Expiry date | Aug 10, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/1098
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.