TDP-43 specific binding molecules
US10259866B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 4, 2016 |
| Grant date | Apr 16, 2019 |
| Priority date | — |
| Expiry date | Nov 4, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2814
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are TAR DNA-binding protein of 43 kDa (TDP-43)-specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, kits, and solid supports related to TDP-43-specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.