Patent · US Active

System and method for confounder-corrected T1 measures using MRI

US10261152B2 · kind B2 · utility

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39Claims
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Key dates

Filing dateMar 22, 2017
Grant dateApr 16, 2019
Priority date
Expiry dateMay 19, 2037

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01R33/5616
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A system and method are provided for determining B1 inhomogeneities or creating a T1 map of a subject using a magnetic resonance imaging (MRI) system that is corrected for an influence of a presence of fat and a presence of iron in the subject on T1 weighting. The method includes controlling the MRI system using a single pulse sequence to acquire, from the subject, a plurality of datasets with varied T1 weighting created by varying at least one of a repetition time (TR) and a flip angle (FA) for repetitions of the single pulse sequence. The method also includes using an MR signal model and the plurality of datasets, estimating B1 inhomogeneities or generating a T1 map of the subject that is corrected for an influence of a presence of fat and a presence of iron in the subject on T1 weighting in the plurality of datasets.

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