Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells
US10265371B2 · kind B2 · utility
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Key dates
| Filing date | Jan 10, 2017 |
| Grant date | Apr 23, 2019 |
| Priority date | — |
| Expiry date | Jan 10, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/62
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conjugates comprising a targeting moiety specific for the CXCR4 and based on the polyphemusin-derived peptide and a therapeutic or imaging agent are provided. Therapeutic and diagnostic methods with the conjugates which require specific targeting to CXCR4+ cells are provided as well.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.