Inhibitor of FLT3 kinase and use thereof
US10266535B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 7, 2015 |
| Grant date | Apr 23, 2019 |
| Priority date | — |
| Expiry date | Aug 7, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.