Chromatography method
US10266563B2 · kind B2 · utility
1Cited by
1References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 4, 2015 |
| Grant date | Apr 23, 2019 |
| Priority date | — |
| Expiry date | Nov 26, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for removal of large contaminants, such as virus, in a chromatographic process for purification of a target molecule, preferably monoclonal antibodies, mAbs, by using a specifically designed chromatographic bead having a thin outer layer and a core functionalized with a ligand adsorbing the mAbs or parts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.