Patent · US Active

Exonuclease deficient polymerases

US10266813B2 · kind B2 · utility

2Cited by
2References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 2017
Grant dateApr 23, 2019
Priority date
Expiry dateFeb 27, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y207/07007
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Described herein are polymerase variants that are exonuclease deficient. Some variants retain the strand displacement capability comparable to the wild-type or parental polymerase. Some variants have a strand displacement capability that is improved relative to the wild-type or parental polymerase. The variants may have an extension rate that is greater than the wild-type or parental polymerase. The variants may have a waiting time that is less than the wild-type or parental polymerase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.