Multimeric coding nucleic acid and uses thereof
US10266843B2 · kind B2 · utility
2Cited by
71References
16Claims
0Family size
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Key dates
| Filing date | Apr 7, 2017 |
| Grant date | Apr 23, 2019 |
| Priority date | — |
| Expiry date | Apr 7, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides, among other things, multimeric coding nucleic acids that exhibit superior stability for in vivo and in vitro use. In some embodiments, a multimeric coding nucleic acid (MCNA) comprises two or more encoding polynucleotides linked via 3′ ends such that the multimeric coding nucleic acid compound comprises two or more 5′ ends.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.