Patent · US Active

Reduction of oxidated methionine peptides for mass spectrometry

US10266866B2 · kind B2 · utility

0Cited by

1References

20Claims

0Family size

Assignee

CALIFORNIA INSTITUTE OF TECHNOLOGY · US

Inventors

Michael J. Sweredoski · Altadena, US
Annie Moradian · Tustin, US
Tanya R. Yakushi · Monterey Park, US
Sonja Hess · Arcadia, US
Roxana Eggleston-Rangel · Los Angeles, US

Key dates

Filing date	Nov 23, 2016
Grant date	Apr 23, 2019
Priority date	—
Expiry date	Nov 23, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y108/04012
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for preparing a methionine containing peptide or protein for analysis by mass spectrometry by incubating the methionine containing peptide or protein with a heterologous methionine sulfoxide reductase A (MsrA), a heterologous methionine sulfoxide reductase B (MsrB), or a heterologous methionine sulfoxide reductase AB (MsrAB) enzyme results in the reduction of an oxidized methionine containing peptide or protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.