Patent · US Active

Method for estimating a retention time in a chromatography column

US10267776B2 · kind B2 · utility

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9Claims

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Assignee

COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES · FR

Inventors

Olivier HARANT · Saint-Égrève, FR
Francois BERTHOLON · Grenoble, FR
Pierre Grangeat · Meylan, FR

Key dates

Filing date	Aug 19, 2016
Grant date	Apr 23, 2019
Priority date	—
Expiry date	Mar 19, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG01N30/6073
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention is a method for estimating a retention time of a particle in a chromatography column, and more particularly in a chromatography column one parameter of which, such as temperature, is modulated. The retention time is estimated on a probabilistic basis by sequentially modelling the transit of the particle in the column. When this stochastic approach is adopted for a set of particles of a given type, it allows a statistical distribution of the retention time in the column to be determined.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.