Combined surface enhanced and spatially offset Raman spectroscopy for biomolecule detection
US10271780B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Nov 23, 2011 |
| Grant date | Apr 30, 2019 |
| Priority date | — |
| Expiry date | Sep 25, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/658
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides systems and methods employing a surface enhanced Raman biosensor and sensing devices for collecting spatially offset Raman spectra from the biosensor. In certain embodiments, the present invention provides systems and methods for quantifying the concentration of an analyte in a subject, and/or identifying the presence or absence of an analyte in a subject, from a plurality of spatially offset Raman spectra generated from a surface enhanced Raman biosensor implanted in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.