Patent · US Active

Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants

US10272103B2 · kind B2 · utility

2Cited by

16References

16Claims

0Family size

Assignee

Relypsa, Inc. · US

Inventors

Jordan Kopping · Redding, US
Paul Mansky · San Francisco, US
YongQi Mu · Los Altos, US
Michael J. Cope · Berkeley, US
Elizabeth Goka · San Jose, US
Angela Lee · San Jose, US
Deidre Madsen · Sunnyvale, US
Jun Shao · Fremont, US
Kalpesh Biyani · Fremont, US
Eric Connor · Los Gatos, US
Scott Hecker · Del Mar, US
Inez Lees · Mountain View, US
Grace May · San Francisco, US
Faleh Salaymeh · Sunnyvale, US
Hongmin Zhang · Santa Clara, US
David E. Bergbreiter · College Station, US

Key dates

Filing date	Oct 30, 2015
Grant date	Apr 30, 2019
Priority date	—
Expiry date	Nov 4, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08F232/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a crosslinked amine and amide polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritis, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.