Chimeric influenza virus-like particles comprising hemagglutinin
US10272148B2 · kind B2 · utility
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20References
17Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 25, 2010 |
| Grant date | Apr 30, 2019 |
| Priority date | — |
| Expiry date | Jun 25, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for synthesizing chimeric influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of chimeric influenza HA in a plant or a portion of a plant. The invention is also directed towards a VLP comprising chimeric influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding chimeric influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.