Design, synthesis and use of synthetic nucleotides comprising charge mass tags
US10273261B2 · kind B2 · utility
2Cited by
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6Claims
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Key dates
| Filing date | Jan 3, 2017 |
| Grant date | Apr 30, 2019 |
| Priority date | — |
| Expiry date | Jan 3, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2560/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.