Crystalline form A of obeticholic acid and preparation method thereof
US10273262B2 · kind B2 · utility
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Key dates
| Filing date | Dec 30, 2015 |
| Grant date | Apr 30, 2019 |
| Priority date | — |
| Expiry date | Dec 30, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to crystalline Form A of obeticholic acid and the preparation method thereof. The present invention provides Form A having characteristic peaks at 2theta value of 4.9°±0.2°, 5.2°±0.2°, 9.9°±0.2°. The present invention provides a novel crystalline form of obeticholic acid, which has good stability, good processability and other favorable properties, and is suitable for storage and usage as a final product. In addition, the preparation method is simple, low cost, and has great value for the future optimization and development of obeticholic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.