Patent · US Active

Perfusion manifold assembly

US10273441B2 · kind B2 · utility

1Cited by

2References

42Claims

0Family size

Assignee

EMULATE, INC. · US

Inventors

Daniel Levner · Brookline, US
Josiah Daniel Sliz · Boston, US
Christopher David Hinojosa · Cambridge, US
Guy Thompson, II · Watertown, US
Petrus Wilhelmus Martinus van Ruijven · Melbourne, AU
Matthew Daniel Solomon · Melbourne, AU
Christian Alexander Potzner · Melbourne, AU
Patrick Tuohy · Melbourne, AU
Joshua Gomes · Somerville, US
Norman Wen · Dedham, US
Jacob Freake · Somerville, US
Doug Sabin · Marblehead, US

Key dates

Filing date	Aug 26, 2016
Grant date	Apr 30, 2019
Priority date	—
Expiry date	Aug 9, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2521/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a perfusion manifold assembly that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with an assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate. The invention further relates to a drop-to-drop connection scheme for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.