Methods of determining an analyte concentration in a body fluid sample, as well as analytical devices and systems for use therein

US10274430B2 · kind B2 · utility

Assignee

• Roche Diabetes Care, Inc. · US

Inventors

• Gertrud Albrecht · Mannheim, DE
• Edgar Baumann · Mannheim, DE
• Markus Genthner-Riegler · Heidelberg, DE
• Stefan Kalveram · Viernheim, DE
• Christian Niesporek · Heidelberg, DE
• Kai-Oliver Schwenker · Haßloch, DE
• Markus Serr · Zug, CH
• Frederic Wehowski · Hockenheim, DE
• Klaus Wettengel · Flörsheim-Dalsheim, DE

Key dates

• Filing date: May 4, 2016
• Grant date: Apr 30, 2019
• Expiry date: Jul 1, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/0697
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods, analytical devices and analytical systems are provided for determining at least one analyte concentration in a body fluid sample. The methods, which may be incorporated into the devices and systems, can include the following steps: applying a body fluid to a test carrier; illuminating the test carrier by at least one light source, where the at least one light source is modulated by using at least two modulation frequencies; receiving light remitted by the test carrier by using at least one detector; determining an analyte concentration by evaluating at least one detector signal generated by the detector, where the detector signal is demodulated with the at least two modulation frequencies to generate at least two demodulated detector signals, each demodulated signal corresponding to one of the modulation frequencies; and detecting a fault by comparing the at least two demodulated detector signals.