Compositions and methods for spinal disc repair and other surgical and non-surgical indications

US10279079B2 · kind B2 · utility

Assignee

• The Research Foundation for The State University of New York · US

Inventors

• Raphael Davis · Port Jefferson, US
• Divya Bhatnagar · Stony Brook, US
• Miriam Rafailovich · Plainview, US

Key dates

• Filing date: Jul 5, 2012
• Grant date: May 7, 2019
• Expiry date: Jul 27, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/38
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The present invention features, inter alia, biocompatible compositions that include a poloxamer and one or more additives such as hyaluronic acid, gelatin, fibronectin, or a peptide fragment of fibronectin. The compositions are useful in tissue repair or remodeling, including repair of an injured spinal disc, in drug delivery, in cell culture, and in inhibiting the formation of adhesions.