Patent · US Active

Method for the synthesis of aminoalkylenephosphonic acid

US10280189B2 · kind B2 · utility

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27References
26Claims
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Key dates

Filing dateJul 17, 2013
Grant dateMay 7, 2019
Priority date
Expiry dateMar 19, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/653
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method for the synthesis of an aminoalkylenephosphonic acid or its phosphonate esters including the following steps: a) forming, in the presence of an aldehyde or ketone and an acid catalyst, a reaction mixture by mixing a compound having at least one HNR1R2 moiety or a salt thereof, with a compound having one or more P—O—P anhydride moieties, the moieties having one P atom at the oxidation state (+III) and one P atom at the oxidation state (+III) or (+V), wherein the ratio of moles of aldehyde or ketone to N—H moieties is 1 or more and wherein the ratio of N—H moieties to P—O—P anhydride moieties is 0.3 or more, and b) recovering the resulting aminoalkylenephosphonic acid having compound or its phosphonate esters.

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