Process for preparation of nitrogen mustard derivatives
US10287316B2 · kind B2 · utility
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26Claims
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Assignee
Inventors
Key dates
| Filing date | May 6, 2016 |
| Grant date | May 14, 2019 |
| Priority date | — |
| Expiry date | May 6, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The invention further provides intermediate compounds formed in the process of the invention, and processes for the production of intermediate compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.