Microorganisms for succinic acid production

US10287558B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Joanna Martyna Krawczyk · Mannheim, DE
• Stefan Haefner · Speyer, DE
• Hartwig Schröder · Nümbrecht, DE
• Esther Dantas Costa · Mannheim, DE
• Oskar Zelder · Speyer, DE
• Gregory Von Abendroth · White Plains, US
• Christoph Wittmann · Saarlouis, DE
• René Stellmacher · Binningen, CH
• Judith Becker · Riegelsberg, DE
• Anna Lange · Braunschweig, DE
• Benjamin J. Lyons · Gainesville, US
• Thomas J. Lyons · Gainesville, US
• Eudes De Crecy · Gainesville, US
• Ewa Hughes · Gainesville, US

Key dates

• Filing date: Feb 2, 2015
• Grant date: May 14, 2019
• Expiry date: Feb 2, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y207/0104
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene. The present invention also relates to a method for producing an organic compound and to the use of modified microorganisms.