Polyphosphate-functionalized inorganic nanoparticles as hemostatic compositions and methods of use

US10293077B2 · kind B2 · utility

Assignees

• The Regents of the University of California · US
• The Board of Trustees of the University of Illinois · US

Inventors

• Damien Kudela · Lompoc, US
• Galen D. Stucky · Goleta, US
• Anna May-Masnou · Barcelona, ES
• Gary Bernard Braun · San Diego, US
• James H. Morrissey · Oklahoma City, US
• Stephanie A. Smith · Champaign, US

Key dates

• Filing date: Oct 14, 2015
• Grant date: May 21, 2019
• Expiry date: Oct 14, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2982
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A hemostatic composition is provided. The hemostatic composition includes a hemostatically effective amount of a hemostatic agent that includes a nanoparticle and a polyphosphate polymer attached to the nanoparticle. Also provided are medical devices and methods of use to promote blood clotting.