Patent · US Active

Propyl cationic peptide lipids, synthesis method thereof, and application thereof

US10294199B2 · kind B2 · utility

0Cited by

0References

11Claims

0Family size

Assignee

DALIAN NATIONALITIES UNIVERSITY · CN

Inventors

Shubiao Zhang · 东风镇, CN
Yinan Zhao · Shanghai, CN
Shaohui Cui · 东风镇, CN
Defu Zhi · 东风镇, CN
Hua Hai · 东风镇, CN

Key dates

Filing date	Jun 25, 2015
Grant date	May 21, 2019
Priority date	—
Expiry date	Jul 7, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/88
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A class of propyl cationic peptide lipids is propyl cationic peptide lipid compounds having a general formula structure as follows. After the propyl cationic peptide lipids are dispersed in water, a cationic liposome with a particle size of approximately 100 nm is obtained. The cationic liposome can carry plasmid DNA (pDNA) or small interfering RNA (siRNA) into cells to realize the function of gene delivery, and is almost non-toxic to the cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.