Bendamustine derivatives and related compounds, and medical use thereof in cancer therapy

US10294208B2 · kind B2 · utility

Assignee

• SYNBIAS PHARMA AG · CH

Inventors

• Helmut Schickaneder · Eckental, DE
• Christian Schickaneder · Achern, DE
• Armin Buschauer · Berlin, DE
• Stefan Huber · Regensburg, DE
• Michael Limmert · Dresden, DE
• Gunther Bernhardt · Sankt Augustin, DE
• Mathias Lubbe · Dresden, DE
• Harald Hofmeier · Dresden, DE

Key dates

• Filing date: Jul 11, 2017
• Grant date: May 21, 2019
• Expiry date: Jul 11, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C231/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to bendamustine derivatives and related compounds of formula (VII), (VIII) and (IX), and medical uses thereof in particular in cancer therapy.