Methods for modulating angiogenesis of cancers refractory to anti-VEGF treatment
US10294295B2 · kind B2 · utility
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Key dates
| Filing date | Nov 26, 2014 |
| Grant date | May 21, 2019 |
| Priority date | — |
| Expiry date | Nov 26, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for modulating angiogenesis in a cancer or tumor refractory to anti-VEGF, including identifying a cancer cell as being referactory to anti-VEGF, and then contacting the cancer cell refractory to anti-VEGF with an effective amount of an agent that modulates interaction between Gal1 or a Gal1 fragment and the natural binding partner of Gal1 or the Gal1 fragment to thereby modulate angiogenesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.