Nasolacrimal drainage system implants for drug therapy

US10300014B2 · kind B2 · utility

Assignee

• Mati Therapeutics, Inc. · US

Inventors

• Eugene de Juan, Jr. · San Francisco, US
• Cary J. Reich · Los Gatos, US
• Stephen Boyd · Murrieta, US
• Hanson S. Gifford, III · Woodside, US
• Mark Deem · Mountain View, US
• Alan R. Rapacki · Redwood City, US

Key dates

• Filing date: Oct 23, 2018
• Grant date: May 28, 2019
• Expiry date: Oct 23, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2250/0087
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.