Nanoparticle delivery compositions
US10300022B2 · kind B2 · utility
1Cited by
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3Claims
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Assignee
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Key dates
| Filing date | Feb 7, 2014 |
| Grant date | May 28, 2019 |
| Priority date | — |
| Expiry date | Feb 22, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/93
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nanoparticle delivery systems for use in targeting biologically active agents to the central nervous system comprise a composition comprising (a) a nanoparticle comprising: (i) a core comprising a metal and/or a semiconductor; and (ii) a corona comprising a plurality of ligands covalently linked to the core, wherein said ligands comprise a carbohydrate, insulin and/or a glutathione; and (b) the at least one agent to be delivered to the CNS. Methods of treatment and diagnosing CNS disorders utilizing the nanoparticle delivery systems and related screening methods are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.