Stabilized assembled nanostructures for delivery of encapsulated agents
US10300023B1 · kind B1 · utility
5Cited by
4References
30Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 27, 2018 |
| Grant date | May 28, 2019 |
| Priority date | — |
| Expiry date | Apr 27, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-covalently assembled hydrogel or organo-gel composition with serum stability is described. Low molecular weight (<2,500 Da), generally regarded as safe (GRAS), materials assemble in the presence of a stabilizing agent at an appropriate molar percentage, forming hydrogel or organo-gel with nanostructures that resist disassembly or destabilization in serum for an extended period of time. The composition is used to deliver one or more therapeutic, prophylactic, or diagnostic agents, allowing for controlled release in response to biological stimuli such as enzymes and a greatly improved dosing efficacy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.