Patent · US Active

Method of removing DNA from biotechnological products

US10301588B2 · kind B2 · utility

0Cited by

3References

12Claims

0Family size

Assignee

BASF SE

Inventors

Birgit Hoff · Ludwigshafen, DE
Stefan Haefner · Speyer, DE
Weol Kyu Jeong · Heidelberg, DE
Edzard Scholten · Mannheim, DE

Key dates

Filing date	Dec 9, 2015
Grant date	May 28, 2019
Priority date	—
Expiry date	Dec 9, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2523/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a method for degrading DNA in a sample obtained by microbial fermentation or biotransformation, comprising treating the sample with a combination of increased temperature and low pH. It also relates to a method for releasing DNA from a microbial cell, comprising incubating the microbial cell at a temperature of 45° C. to 55° C. for two to ten hours. Finally, the present invention provides a method for producing a product, comprising a step of releasing DNA from a microbial cell and degrading said DNA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.